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Occlusion of the main iliac artery
The etiologies of iliofemoral artery occlusion and stenosis include arterial stenosis, atherosclerosis, multiple arteritis and recurrent arterial stenosis after surgery. Within clinical practice, patients often present with lower limb ischemia symptoms such as lower limb numbness, hypothermia, and intermittent claudication, etc… In severe cases, patients may present with persistent pain of the lower limb with the dorsal foot artery most commonly affected. Gangrene and other infections may occur with total occlusion.  
In the past, clinical treatment of iliofemoral artery occlusion stenosis often adopted medical and surgical treatment methods. The main medical treatment option is vascularization and anticoagulation. Surgical treatment is mostly appropriate in individual for whom medical treatment did not have effect and for patients with severe vascular stenosis and occlusion. Treatment methods mostly include arterial endarterectomy and arterial bypass grafting. Surgical treatment, especially bypass grafting, was satisfactory with a patency rate of 80-90% in 5 years. Common complications include infection, pseudoaneurysm of anastomosis and peripheral nerve injury.
With the development of interventional radiology in recent years, interventional therapy for peripheral and limb arterial stenosis has been accepted more and more clinically due to its small trauma, rapid recovery, and significant curative effect. 
The main methods of interventional therapy are local embolization, percutaneous angioplasty (PTA) and internal stent implantation. Treatment was initially reserved for symptomatic, short segment, isolated stenosis or occlusion. However, with continuous improvement of interventional techniques and equipment in recent years, long segment cases with multiple atherosclerotic plaques and fresh thrombosis have gradually become one of the indications. Results suggest significant immediate efficacy. Attention should be paid to adequate and timely anticoagulant thrombolysis therapy during and after the operation. 
The PTA curative effect was related to the anatomy of the diseased vessels. The primary success rate was 95%, and the 5-year patency rate was about 90%. For instance, the initial success rate of angioplasty is about 89% for long-segment iliac artery stenosis, and the 5-year patency rate is about 65%. For femoral artery short-segment stenosis, over 90% of patients can be dilated and the 5-year patency rate is about 75%. For long lesions, initial success rate may be higher, but restenosis rate is also higher. 
 
针对疾病
AGAINST DISEASE
 

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